Welcome to Griffith Open
Griffith Open collects, preserves and makes freely available research publications by Griffith College staff and learners. These can include, but are not limited to, theses, peer-reviewed articles, book chapters, working papers and conference papers, professional presentations, exhibitions and teaching resources. Where material has already been published it is made available subject to the open-access policies of the original publishers. This service is maintained by Griffith College Library.
Recent Submissions
The Impact of AI (Machine Learning and Automation) on Biopharmaceutical Manufacturing Industry
(Innopharma, 2024) Sayal, Ruchi
This research investigates the transformative effects of artificial intelligence (AI),
machine learning (ML), and automation on the biopharmaceutical manufacturing
industry. The study provides a comprehensive analysis of how these advanced
technologies are revolutionizing manufacturing processes. Through an extensive
literature review and detailed survey analysis, the research examines how these
technologies address challenges such as data quality and complex biological systems,
emphasizing their role in overcoming regulatory hurdles and improving manufacturing
efficiency. The study explores key trends and drivers behind the escalating adoption of
AI, including the need for process optimization, advancements in drug discovery, and
enhanced quality control.
Furthermore, the research assesses the impact of AI on traditional biopharmaceutical
manufacturing models. It illustrates how AI disrupts conventional processes by
enabling real-time issue identification, enhancing quality control, and boosting
productivity. The introduction of new methodologies such as personalized medication
production, AI-powered robotics, and AI-assisted drug discovery showcases the
transformative potential of these technologies.
In conclusion, the study reveals that AI adoption in the biopharmaceutical industry is
rapidly advancing, driven by its transformative potential in enhancing efficiency,
innovation, and competitiveness. Addressing challenges and ensuring responsible
adoption will be pivotal in realizing the full benefits of AI-enabled technologies in
biopharmaceutical manufacturing. The research provides valuable insights for industry
stakeholders, guiding strategic decision-making and fostering a more informed
approach to integrating AI technologies, ultimately contributing to the growth and
advancement of the biopharmaceutical sector.
Unleashing patient empowerment in Indian healthcare through mobile applications: A critical analysis of user engagement and health outcome
(Innopharma, 2024) Kozhappamadathil Lohithakshan, Unnimaya
Objective: The research objectives include evaluating the adoption and effectiveness of mHealth apps, analysing user engagement metrics, exploring their impact on patient access to health information, measuring the correlation between user engagement and health outcomes, and identifying unique challenges and opportunities in India's mHealth implementation. Methodology: The data was collected through surveys which collected information about the opinions and expectations of healthcare professionals, patients, and other end users of mobile health apps in India, which was distributed through LinkedIn and other professional social networks. A structured questionnaire was prepared by means of Google Forms which included both open-ended and closed-ended questions. The responses from primary research were compared with the secondary sources. Result: The study revealed key insights into mobile healthcare app usage in India. Health metrics tracking was universally important, especially among 26-35-year-olds. Personalized health info mattered to 18-25 and 46-55-year-olds, while health education was crucial for 26- 35 and 56+ age groups. Remote consultations were valued by 26-35 and 36-45-year-olds, with peak usage in the 26-35 group. Challenges like technical issues and data privacy affected all ages, with integration problems for 26-35 and 36-45-year-olds, and comprehension issues for 18-25 and 46-55-year-olds. Occupation influenced usage patterns, with employed nonhealthcare pros using apps the most, followed by healthcare pros and students. Customizable features, enhanced privacy, and local service integration were key across all occupations. Recommendations included collaboration with healthcare professionals and government support. Addressing demographic-specific barriers is crucial for improving engagement and health outcomes nationwide. Conclusion: Despite the widespread recognition of the benefits of mobile healthcare applications in India, significant barriers remain that hinder their full potential. While health metrics tracking and personalized health information are valued across various age and occupational groups, issues such as technical difficulties, internet connectivity, and data privacy concerns continue to pose challenges. Addressing these issues, along with improving the integration of mHealth apps into existing healthcare systems and enhancing user comprehension, is essential. Tailored strategies that consider age, gender, and occupation specific needs can bridge the gap between current usage and optimal functionality. Collaborative efforts between app developers, healthcare professionals, and policymakers, supported by government initiatives and emerging technologies, are crucial for enhancing the adoption and effectiveness of mHealth applications, ultimately leading to better health outcomes in India. Further research is needed to evaluate and refine these strategies, ensuring they meet the diverse needs of the Indian population.
Ensuring Product Quality in Irish Biologic and Biopharmaceutical Logistics through IoT-enabled Cold Chain Monitoring
(Innopharma, 2024) Manikantan Nair, Nisha
The fourth industrial revolution along with the advancement in digital technologies have revolutionized the realm of biologics and biopharmaceutical logistics. This dissertation embarks on a journey to explore the integration of Internet of things (IoT) enabled technologies in cold chain monitoring within the Irish biologic and biopharmaceutical logistics sector. The study focuses on ensuring the quality and safety of temperature-sensitive biologics and biopharmaceutical products like gene therapies, monoclonal antibodies, vaccines, diagnostic kits and reagents during storage and transportation till it reaches the end customer. The study is relevant especially for a country like Ireland renowned for being one of the leading global hubs in biopharmaceuticals, medical device technology and digital health technology. The biologic and biopharmaceutical logistics industry of Ireland rely heavily on efficient and reliable cold chain monitoring to ensure the quality, safety, and efficacy of temperature sensitive medications, vaccines, and biologics. The ever-increasing demand for vaccines, gene therapies, monoclonal antibodies, and biomedical products like diagnostic reagents and medical laboratory supplies post COVID-19 pandemic has made it important to maintain the optimal storage conditions throughout their transit within the supply chain. Industry 4.0 technologies like the Internet of things (IoT) can be a game changer in the cold chain logistics through its capabilities in offering real-time monitoring of temperature and other environmental factors like humidity, pressure, etc. Through time-monitoring, anomalies in temperature and other environmental factors can be detected immediately and immediate measures can be taken to prevent any adversities, thus ensuring the safety and efficacy of the product.
This research further aims to emphasise the understanding of available IoT technologies having the potential to transform the biologic and biopharmaceutical cold chain, thus enhancing product quality and ensuring patient safety.
Evaluating the impact of electronic prescription services on workflow efficiencies in community pharmacies of Dublin, Ireland.
(Innopharma, 2024) Vattamkandathil Tomy, Ardra
The integration of Electronic Prescription Services (EPS) represents a significant advancement in the healthcare sector, designed to enhance the accuracy and efficiency of prescription management. By enabling the electronic transmission of prescriptions from healthcare providers to pharmacies, EPS aims to reduce the errors associated with traditional paper-based prescriptions and streamline pharmacy operations. Despite its potential benefits, the implementation of EPS presents various challenges, including technical integration and the need for comprehensive staff training.
This research investigates the impact of Electronic Prescription Services (EPS) on community pharmacies in Dublin, Ireland, examining areas such as prescription
accuracy, workflow efficiency, pharmacist satisfaction, and implementation challenges. EPS, an advancement in healthcare, facilitates the electronic transmission
of prescriptions from healthcare providers to pharmacies, aiming to enhance patient safety, streamline operations, and reduce errors compared to traditional paper
prescriptions. Despite EPS’s potential benefits, including improved prescription accuracy and operational efficiency, community pharmacies face challenges such as
technical integration issues and the need for effective staff training. This study employs a quantitative methodology, using surveys distributed to pharmacists and
pharmacy staff, to evaluate these impacts comprehensively.
Adopting a pragmatic research philosophy and an inductive approach, the study collects and analyzes primary data to understand the operational changes brought about by EPS. Data analysis, performed using JASP software, involved descriptive and inferential statistical techniques, including Chi-square and Kendall’s Tau tests, to assess relationships between EPS implementation and various performance metrics.
The findings reveal significant associations: improved communication with prescribers correlates moderately with reduced prescription errors, and overall pharmacist satisfaction is strongly associated with the ease of EPS use and improvements in medication inventory management. Workflow efficiency showed notable improvements in prescription processing time, daily volume, patient waiting
time, and counselling ability, though increased processing time was linked to reduced efficiency. Confidence in EPS is high, particularly regarding its role in identifying potential medication interactions.
The study concludes that EPS positively impacts several facets of pharmacy operations, enhancing prescription accuracy, workflow efficiency, and pharmacist
satisfaction, while increasing confidence in the system. Nonetheless, further attention is needed to address training and technical challenges associated with EPS
implementation.
Assessment of impact of digital revolution on prescription legibility and dispensing efficiency in community pharmacies in India
(Innopharma, 2024) Vinodkumaar, Govind
The research analyses pharmacists' opinions about the implementation of electronic prescribing systems and investigates at the frequency and effects of illegible prescriptions in community pharmacies in Kerala, India. A survey comprising both closed-ended and open-ended questions was administered to 105 registered pharmacists in order to collect data. For the quantitative and qualitative data, respectively, descriptive statistics and thematic analysis were used. The survey shows that prescriptions that are difficult to read is a common problem; 80.8% of pharmacists identify things like poor handwriting, unclear symbols, and missing information. Of the respondents, over half (48.1%) received illegible prescriptions once in a while, and 25% received them frequently. Readability issues with these prescriptions were identified by the vast majority (97.1%), which resulted in processing errors (67.3%), possible patient damage (56.7%), and decreased workflow efficiency (48.1%). When presented with illegible prescriptions, pharmacists frequently consulted colleagues (33.7%) or contacted prescribers (63.5%) for clarification. The most common outcome of illegible prescriptions was found to be dispensing errors (64.4%). Improved understanding (38.5%), reduced mistake rates (33.7%), and increased workflow efficiency (23.1%) are only some of the benefits of electronic prescription systems that the report reveals. The majority of pharmacists supported the switch to electronic prescription, even though they mentioned possible difficulties such technological issues (73.1%) and problems during system failures (13.5%). Benefits including improved patient safety, more efficient workflow, and reduced administrative load were highlighted. The study's findings emphasize how critical it is to address prescription legibility in order to enhance patient safety and pharmacy efficiency. It is suggested that electronic prescription systems be implemented as a realistic approach, given that sufficient technical assistance and training are provided.