eprintid: 506 rev_number: 14 eprint_status: archive userid: 30 dir: disk0/00/00/05/06 datestamp: 2022-01-19 21:41:31 lastmod: 2022-01-19 21:41:31 status_changed: 2022-01-19 21:41:31 type: thesis metadata_visibility: show creators_name: Olatokunbo, Ojo Nathaniel corp_creators: Supervisor: Dr. Alessandra Vecchi title: The Study of the Key Challenges Facing Pharmaceutical Manufacturing Industry in Lagos, Nigeria, With Emphasis on Cost and Access to Quality Raw Material ispublished: submitted subjects: RS divisions: MScPBT full_text_status: public abstract: The Nigerian pharmaceutical manufacturing industry is very important to the economy of Nigeria. From empirical research already done on the Nigerian pharmaceutical industry, it was gathered that several challenges drag the development of the sector. This gave good understanding about this work which aims to study the challenges facing the pharmaceutical manufacturing industry in Lagos, Nigeria with emphasis on cost and access to quality raw materials. Considerably, 25% of the pharmaceutical products required by Nigerians are locally delivered by Nigeria’s pharmaceutical industry. The excess 75% are imported from other developed nations like UK, India and China (WHO/PQT, 2014). The Research Onion proposed by Saunders and his colleagues Lewis and Thornhill in 2009 forms the bases and provides the structure for the research process used in this study. Central in the context of this dissertation is the research philosophy of interpretivism. The research approach was deductive and aimed to collect data and build a theory based on the results (Saunders, Lewis and Thornhill, 2009). A case study strategy was used to properly understand the challenges especially in the area of cost and access to quality raw materials, facing the four pharmaceutical manufacturing firms employed in this study. A mono method research choice (only qualitative research strategy) was adopted for the collection of data. Then data were collected and analysed into themes which assisted in the overall research findings. The results from this study on the accessibility of raw material reveal that all the pharmaceutical firms in Nigeria rely heavily on the importation of raw materials. On the affordability of quality raw materials, all data collected pointed to the fact that the prices of quality materials are becoming increasingly expensive and unaffordable. On the impact of accessibility to quality raw materials on the production capacity, this study revealed that accessibility to quality materials dramatically influences the production capability of pharmaceutical firms in Nigeria. Lastly, on the impact of cost of quality raw materials on the production capacity, this study revealed that the cost of the materials is prohibitive. date: 2021 date_type: completed institution: Innopharma department: Innopharma Faculty Of Pharmaceutical Science thesis_type: masters referencetext: (1) = Product weight ⁄ Incoming material weight However, industrial material input data are not always precise, which leads to equation 2. Material efficiency = Product output ⁄ (Generated waste + Produced product) Eqn. (2) = Product weight ⁄ Incoming material weight However = Product weight ⁄ (Waste weight + Product weight) These criteria can also be indexed per unit produced, per production or per tonne of products. It is also possible to utilize cost equivalents or volume measures (Kurdve, 2008), as shown in equation 3. Material efficiency = Product value ⁄ (Waste cost + Product value) Eqn. (3) Moreover, material efficiency is related to economy, and economical efficiency is measured in terms of money. Thus, equations 4 and 5 can be written as suggested by Allwood et al. (2013). Materials required/Service provided = Materials required ⁄ Money spent × Money spent ⁄ Service provided Eqn. (4) Physical material efficiency = Economic material efficiency × Price of service Eqn. (5) All of these measures consider total material efficiency, including product material. Because the focus of this thesis is on residual material, efforts were made to identify literature on material efficiency that addresses residual material. However, there is scant research on material efficiency in the manufacturing industry that addresses the segregation of residual material. 2.8 EMPIRICAL RESEARCH ON PERFORMANCE CAPABILITY OF PHARMACEUTICAL INDUSTRIES IN NIGERIA The Nigerian pharmaceutical industry which is perceived to be diverse includes manufacturers, national regulators, wholesalers and retailers, government ministries and other stakeholders (Obohokwo et al., 2018). In order to truly appreciate the sector's potential, these stakeholders must make additional efforts to create an enabling environment. The Nigerian pharmaceutical industry according to the Pharmaceutical Manufacturers Group of the Manufacturers Association of Nigeria (PM citation: Olatokunbo, Ojo Nathaniel (2021) The Study of the Key Challenges Facing Pharmaceutical Manufacturing Industry in Lagos, Nigeria, With Emphasis on Cost and Access to Quality Raw Material. Masters thesis, Innopharma. document_url: http://go.griffith.ie/506/1/10360_Nathaniel_Olatokunbo_Ojo_RESEARCH_DISSERTATION_148435_311713269.pdf