eprintid: 501 rev_number: 9 eprint_status: archive userid: 30 dir: disk0/00/00/05/01 datestamp: 2022-01-17 11:42:00 lastmod: 2022-01-17 11:42:00 status_changed: 2022-01-17 11:42:00 type: thesis metadata_visibility: show creators_name: Mathew, Athul corp_creators: Supervisor: Kathy Clarke title: Antidepressants among Healthcare Professionals in South India ispublished: submitted subjects: RS divisions: MScPBT full_text_status: public keywords: Antidepressant abuse and overuse, Self-Medication of Antidepressants abstract: 1.Background Antidepressants are drugs which are used to relieve the symptoms of depressive disorders. The clinical awareness about physical, mental and social factors of a patient is very keen in deciding an optimal antidepressant therapy. The rational use of antidepressant must be monitored very carefully as inappropriate use can lead to its abuse and overuse 2. Purpose This study aims to evaluate the knowledge and attitude towards, antidepressant drugs among the healthcare professionals working in South India. This is to analyse the issues involved in practicing antidepressant therapy and review the methods to ameliorate and enhance the implementation of antidepressants. 3. Design and methodology The study involved deductive approach as well as qualitative and quantitative analysis was done for the questionnaire-based survey conducted among 50 healthcare professionals in South India. The secondary data was acquired from an analysis of current research articles on antidepressants and its abuse and overuse and the measures to curtail these issues. 4. Findings Eighty four percent of the participants reported that the main cause for antidepressant abuse and overuse is the inappropriate use of antidepressants. Considering, pharmaceutical companies’ intervention, there was a strong agreement from the study group at seventy four percent while twenty four percent gave a neutral response. A large proportion of the healthcare professionals agree that outpatients pressurise them to prescribe or dispense antidepressants. 5. Conclusion The participants had adequate understanding of general antidepressant use. Lack of knowledge can be curtailed by the implementation of antidepressant awareness programs. Healthcare professionals should be motivated to attend training programmes to reduce the abuse and overuse of antidepressants. date: 2021 date_type: completed institution: Innopharma department: Innopharma Education thesis_type: masters referencetext: ................................................................................................. 58 LIST OF FIGURES Abbas, A. et al. (2015) (3) ‘Prevalence of Self-Medication of Psychoactive Stimulants and Antidepressants among Undergraduate Pharmacy Students in Twelve Pakistani Cities'. Tropical Journal of Pharmaceutical Research, 14(3), pp. 527-532. DOI: 10.4314/tjpr.v14i3.23. Bhandari, P. (2020) Data Collection | A Step-by-Step Guide with Methods and Examples. Scribbr. Available at: https://www.scribbr.com/methodology/datacollection/ (Accessed: 3 June 2021). Bhandari, P. (2021) What Is Quantitative Research? | Definition, Uses and Methods. Available at: https://www.scribbr.com/methodology/quantitativeresearch/ (Accessed: 26 May 2021). Bhandari, S. (2019) Antidepressants: Fears and Facts. WebMD. Available at: https://www.webmd.com/depression/fears-and-facts-about-antidepressants (Accessed: 22 April 2021). Botega, N.J. and Silveira, G.M. (2015) ‘General Practitioners Attitudes towards Depression: A Study in Primary Care Setting in Brazil'. The International Journal of Social Psychiatry, 42(3), pp. 230-237. DOI: 10.1177/002076409604200307. Brown, R.C.H. and Savulescu, J. (2019) ‘Responsibility in Healthcare across Time and Agents'. Journal of Medical Ethics, 45(10), pp. 636-644. DOI: 10.1136/medethics-2019-105382. Correa, D. (2020) Antidepressant Drugs Market to Grow Valuation of $15.98 Billion by 2023. GlobeNewswire News Room. Available at: https://www.globenewswire.com/newsrelease/2020/08/06/2074356/0/en/Antidepressant-Drugs-Market-to-Grow Valuation-of-15-98-Billion-by-2023.html (Accessed: 27 April 2021). Crossley, J. (2021) Saunders' Research Onion: Explained Simply (+ Examples) Grad Coach. Available at: https://gradcoach.com/saunders-research-onion/ (Accessed: 26 May 2021). Derrin, A. (2019) Antidepressant Awareness and Stigmatizing Attitudes toward Depression and Antidepressants, a Comparison between First and Sixth-Year Medical Students - Ayşe Derin Nalçakan, Ezgi Aysu Şahin, Oguz Kaan Yalcinkaya, Sertac Ak, 2021. Available at: https://journals.sagepub.com/doi/abs/10.1177/0020764020985545 (Accessed: 27 April 2021). Dunlop, B.W. (2017) (NCT01916824) Effects of Treatment on Decision-Making in Major Depression. Clinicaltrials.Gov Available at: https://clinicaltrials.gov/ct2/show/NCT01916824 (Accessed: 25 May 2021). Ecks, S. (2019) ‘The Unlicensed Lives of Antidepressants in India: Generic Drugs, Unqualified Practitioners, and Floating Prescriptions'. Transcultural Psychiatry, 46(1), pp. 86-106. DOI: 10.1177/1363461509102289. Evans, E. and Sullivan, M. (2014) ‘Abuse and Misuse of Antidepressants'. Substance Abuse and Rehabilitation, 5, pp. 107-20. DOI: 10.2147/SAR.S37917. Floyde, bloom. (2019) Antidepressant. Encyclopedia Britannica. Available at: https://www.britannica.com/science/antidepressant (Accessed: 27 April 2021). Glen, W. (2018) Drug Use - Social and Ethical Issues of Drug Abuse | Britannica. Available at: https://www.britannica.com/topic/drug-use/Social-and-ethicalissues-of-drug-abuse (Accessed: 26 May 2021). Grimm, C. (2021) Why Drug Prescriptions Should Include Diagnoses - STAT. Available at: https://www.statnews.com/2021/03/01/why-drug-prescriptionsshould-include-diagnoses/ (Accessed: 26 May 2021). Hahn, K.L. (2011) ‘Strategies to Prevent Opioid Misuse, Abuse, and Diversion That May Also Reduce the Associated Costs'. American Health & Drug Benefits, 4(2), pp. 107-114. Hieronymus, F. (2019) ‘Which Antidepressant Doses Are Optimal?' The Lancet Psychiatry, 6(7), pp. 552-554. DOI: 10.1016/S2215-0366(19)30221-4. Jilcha, K. (2019) Research Design and Methodology | IntechOpen. Available at: https://www.intechopen.com/books/cyberspace/research-design-andmethodology (Accessed: 3 June 2021). Kasthuri, A. (2018) ‘Challenges to Healthcare in India - The Five A's'. Indian Journal of Community Medicine : Official Publication of Indian Association of Preventive & Social Medicine, 43(3), pp. 141-143. DOI: 10.4103/ijcm.IJCM_194_18. Kehoe, W.A. (2016) ‘Factors Affecting the Use and Selection of Antidepressants in the Elderly'. Expert Review of Neurotherapeutics, 2(1), pp. 35-43. DOI: 10.1586/14737175.2.1.35. Latten, T. et al. (2018) ‘Pharmaceutical Companies and Healthcare Providers: Going beyond the Gift - An Explorative Review'. PLoS ONE, 13(2). DOI: 10.1371/journal.pone.0191856. López-Muñoz, F. (2009) ‘Monoaminergic Neurotransmission: The History of the Discovery of Antidepressants from 1950s until Today'. Current Pharmaceutical Design, 15(14), pp. 1563-1586. DOI: 10.2174/138161209788168001. MacIntosh, K.D.O.R. (2016) ‘Research Philosophy and Paradigm'. In Paterson, A. et al. (eds.) Research Methods for Accounting and Finance. Goodfellow Publishers. DOI: 10.23912/978-1-910158-88-3-3232. Maria, A. (2018) The Problem of Self-Medicating with Antidepressants | Health Coomeva Magazine. Revista Salud Coomeva. Available at: https://revistasaludcoomeva.co/the-problem-of-self-medicating-withantidepressants/ (Accessed: 22 April 2021). Markets, R. and. (2020) Global Antidepressants Market (2020 to 2030) - COVID 19 Implications and Growth. GlobeNewswire News Room. Available at: https://www.globenewswire.com/newsrelease/2020/04/21/2019282/28124/en/Global-Antidepressants-Market-2020 to-2030-COVID-19-Implications-and-Growth.html (Accessed: 27 April 2021). Melinda. (2017) Antidepressant Medication - HelpGuide.Org. https://www.helpguide.org. Available at: https://www.helpguide.org/articles/depression/antidepressantmedication.htm (Accessed: 27 April 2021). Morgan, M.A. et al. (2006) ‘Interactions of Doctors with the Pharmaceutical Industry'. Journal of Medical Ethics, 32(10), pp. 559-563. DOI: 10.1136/jme.2005.014480. Nutting, P.A. et al. (2014) ‘Barriers to Initiating Depression Treatment in Primary Care Practice'. Journal of General Internal Medicine, 17(2), pp. 103-111. DOI: https://doi.org/10.1046/j.1525-1497.2002.10128.x. Osterwis, M. et al. (2017) Roles of Health Professionals and Institutions. National Academies Press (US) Available at: https://www.ncbi.nlm.nih.gov/books/NBK217847/ (Accessed: 27 April 2021). Penn, E. and Tracy, D.K. (2012) ‘The Drugs Don't Work? Antidepressants and the Current and Future Pharmacological Management of Depression'. Therapeutic Advances in Psychopharmacology, 2(5), pp. 179-188. DOI: 10.1177/2045125312445469. Pierre, J. (2018) Abuse of Psychiatric Medications: Not Just Stimulants and Benzodiazepines | MDedge Psychiatry. Available at: https://www.mdedge.com/psychiatry/article/191746/addictionmedicine/abuse-psychiatric-medications-not-just-stimulants-and (Accessed: 27 April 2021). Popa-Velea, O. et al. (2015) ‘Current Challenges and Pitfalls in the Pharmacological Treatment of Depression'. Journal of Medicine and Life, 8(2), pp. 181-186. Purcarea, V.L. (2019) ‘The Impact of Marketing Strategies in Healthcare Systems'. Journal of Medicine and Life, 12(2), pp. 93-96. DOI: 10.25122/jml 2019-1003. Ragab, M.A. and Arisha, A. (2017) (1) ‘Research Methodology in Business: A Starter's Guide'. Management and Organizational Studies, 5(1), p. 1. DOI: 10.5430/mos.v5n1p1. Saunders, M.N.K. et al. (2015) ‘Understanding Research Philosophy and Approaches to Theory Development'. In Saunders, M.N.K.Lewis, P.and Thornhill, A. (eds.) Research Methods for Business Students. Harlow: Pearson Education, pp. 122-161. Available at: http://catalogue.pearsoned.co.uk/educator/product/Research-Methods-forBusiness-Students/9781292016627.page (Accessed: 26 May 2021). Scheerder, G. et al. (2011) ‘Community and Health Professionals' Attitude Toward Depression: A Pilot Study in Nine Eaad Countries'. International Journal of Social Psychiatry, 57(4), pp. 387-401. DOI: 10.1177/0020764009359742. Schneider, J. (2020) Beyond Depression: Other Uses for Tricyclic Antidepressants. Consult QD. Available at: https://consultqd.clevelandclinic.org/beyonddepression-other-uses-for-tricyclic-antidepressants/ (Accessed: 21 April 2021). Shelton, R.C. (2019) ‘Steps Following Attainment of Remission: Discontinuation of Antidepressant Therapy'. Primary Care Companion to The Journal of Clinical Psychiatry, 3(4), pp. 168-174. Shrank, W.H. and Avorn, J. (2007) ‘Educating Patients about Their Medications: The Potential and Limitations of Written Drug Information'. Health Affairs (Project Hope), 26(3), pp. 731-740. DOI: 10.1377/hlthaff.26.3.731. Smith, B. (2012) Inappropriate Prescribing. https://www.apa.org. Available at: https://www.apa.org/monitor/2012/06/prescribing (Accessed: 27 April 2021). Sokol, D.K. (2019) ‘Virulent Epidemics and Scope of Healthcare Workers' Duty of Care'. Emerging Infectious Diseases, 12(8), pp. 1238-1241. DOI: 10.3201/eid1208.060360. Timothy, j. (2018) Antidepressants: Types, Side Effects, Uses, and Effectiveness. Available at: https://www.medicalnewstoday.com/articles/248320 (Accessed: 27 April 2021). Treglia, M. et al. (2018) ‘SSRI Antidepressant Selection and Concomitant Prescribing of Anxiolytics and Sedative-Hypnotics: Evidence from Primary Care in the United Kingdom'. Journal of Medical Economics, 1(1-4), pp. 219-233. DOI: 10.3111/199801219233. Tripathi, A. et al. (2016) ‘Prescription Pattern of Antidepressants in Five Tertiary Care Psychiatric Centres of India'. Indian Journal of Medical Research, 143(4), p. 507. DOI: 10.4103/0971-5916.184289. Vanclay, F. (2013) Full Article: Principles for Ethical Research Involving Humans: Ethical Professional Practice in Impact Assessment Part I. Available at: https://www.tandfonline.com/doi/full/10.1080/14615517.2013.850307 (Accessed: 26 May 2021). Zimmerman, M. et al. (2019) ‘Which Factors Influence Psychiatrists' Selection of Antidepressants?' The American Journal of Psychiatry, 161(7), pp. 1285-1289. DOI: 10.1176/appi.ajp.161.7.1285. citation: Mathew, Athul (2021) Antidepressants among Healthcare Professionals in South India. Masters thesis, Innopharma. document_url: http://go.griffith.ie/501/1/10401_Athul_Mathew_EVALUATION_OF_KNOWLEDGE_AND_ATTITUDE_TOWARDS_ANTIDEPRESSANTS_AMONG_HEALTHCARE_PROFESS_61636961.pdf document_url: http://go.griffith.ie/501/2/bibliography.txt